Doctoral Programs – Integrated and Advanced Medical Course, Graduate School of Medical Sciences, University of Fukui

Admission Policy

Educational ideals/Goals

At the Graduate School of Medicine, University of Fukui, our aim is to cultivate

  1. Medical researchers with high-level knowledge who can scientifically and logically conduct cutting-edge medical research.
  2. Clinical Physicians with the ability to deliver advanced and high-level clinical care.
  3. High level General Practitioners, Emergency Physicians and Family Physicians who have the clinical research ability to contribute to communities and the competence of educational leadership. And our goal is developing human resources and highly specialized professionals play an active role in the society of 21th century.

Expected Student Profile

To accomplish our policies and goals, we seek the following candidates for our doctoral courses

  1. Those who use their scientific and logical thinking skills to conduct high-level research in the fields of medicine and life sciences.
  2. Those who wish to become clinical researchers with advanced and high level clinical abilities in medical fields.
  3. Those who wish to become General Practitioners, Emergency Physicians, or Family Physicians who can conduct research and carry out education.

Selection of Candidates

Our PhD courses welcome applicants whose goal is to pursue activities in medicine and related fields in the future.

  1. Enrollment: Spring (April) and fall (October). Entrance exams are offered twice a year, one for each entrance term.
  2. Qualification of applicants: We will consider applicants who have not majored in medicine, dentistry, pharmacy or veterinary medicine for 6 years, through their qualifications, experience and research history.
  3. Examination: We evaluate the applicant’s language ability and expert knowledge through an English examination and oral examination about their knowledge of their desired field.


Course Introduction of Graduate School

Life Sciences Course

Supervisor Department
IINO Satoshi Anatomy
FUKAZAWA Yugo Brain Structure and Function
MATSUOKA Satoshi Integrative Systems Physiology
SADA Kiyonao Genome Science and Microbiology
SUGAI Manabu Molecular Genetics
YAMADA Masami Cell Biology and Biochemistry
AOKI Kouji Pharmacology
FUJITA Ryousuke Biostatistics
IWAMOTO Masayuki Molecular Neuroscience
KIDOYA Hiroyasu Integrated Vascular Biology
OKAZAWA Hidehiko Medical Imaging Division, Biomedical Imaging Research Center
KIYONO Yasushi Molecular Imaging Division, Biomedical Imaging Research Center

Advanced Biomedical Sciences Course

Oncology Section

Supervisor Department
KOBAYASHI Motohiro Tumor Pathology
YAMAUCHI Takahiro First Department of Internal Medicine
GOI Takanori First Department of Surgery
YOSHIDA Yoshio Obstetrics and Gynecology
HASEGAWA Minoru Dermatology
YOSHIMURA Hitoshi Dentistry and Oral Surgery
IWASAKI Hiromichi Division of Infection & Clinical Immunology, University of Fukui Hospital
SAKAMAKI Ippei Infectious Diseases

Regenerative Medicine Section

Supervisor Department
NAKAMOTO Yasunari Second Department of Internal Medicine
ISHIZUKA Tamotsu Third Department of Internal Medicine
IWANO Masayuki Nephrology, Laboratory Medicine
TADA Hiroshi Cardiovascular Medicine
OHSHIMA Yusei Pediatrics
KOSAKA Hirotaka Neuropsychiatry
KOSHIJI Takaaki Second Department of Surgery
MATSUMINE Akihiko Orthopedics and Rehabilitation Medicine
SHIGEMI Kenji Anesthesiology and Reanimatology
YOKOYAMA Osamu Urology
KIKUTA Ken-ichiro Neurosurgery
INATANI Masaru Ophthalmology
FUJIEDA Shigeharu Otorhinolaryngology – Head and Neck Surgery
MORIOKA kouichi Department of Patient Safety, Center for Patient Safety and Infection Control, University of Fukui Hospital

Medical Information of Pathophysiology Section

Supervisor Department
NAIKI Hironobu Molecular Pathology
HIRAKU Yusuke Environmental Health
SHIMADA Ichiro Forensic Medicine and Human Genetics
KIMURA Hirohiko Radiology
GOTO Nobuyuki Department of Pharmacy, University of Fukui Hospital

Comprehensive Community Medicine Course

Supervisor Department
HAYASHI Hiroyuki Emergency Medicine
YAMAMURA Osamu Community Medicine
IKAI Tomoki Primary Health Care

Latest Doctoral Dissertation

Conductance Selectivity of Na+ Across the K+ Channel via Na+ Trapped in a Tortuous Trajectory
Proteins have generally complicated structures, and to understand the mechanism of their function, approaches to getting into the nano-world are prerequisites. Potassium channels ubiquitous in cell membranes have a strict selectivity for larger K+ over smaller Na+, and the mechanism underlying the selectivity is described in the standard textbooks. We applied nano-world tools, such as single-molecule measurements and molecular dynamics simulation. We refuted the previous interpretation by showing that Na+ substantially permeates across the potassium channel for the first time. In the computer simulation, smaller Na+ is trapped in small pits here and there along the pore, leading to slow elution. On the other hand, larger K+ took a straight pass by ignoring pits. A novel ion selectivity mechanism via differential permeation rates through different trajectories is proposed.
MITA Kenichiro (2020 graduated in fiscal year)
Influences of Folate Supplementation on Homocysteine and Cognition in Patients with Folate Deficiency and Cognitive Impairment
Among 1349 participants who visited the dementia outpatient clinic between, 45 patients with folate deficiency and cognitive impairment were enrolled. Folate supplementation significantly improved plasma homocysteine (Hcy) levels from 25.0 ± 18.0 to 11.0 ± 4.3 nmol/mL (p<0.001). MMSE scores also significantly changed from 20.1 ± 4.7 to 22.2 ± 4.3 (p<0.001). The degree of change in the MMSE score and degree of hippocampal atrophy in MRI was not correlated. Folate supplementation ameliorated cognitive impairment in patients with folate deficiency regardless of hippocampal atrophy.
HAMA Yuka (2020 graduated in fiscal year)
Evaluation of Bleb Fluid After Baerveldt Glaucoma Implantation Using Magnetic Resonance Imaging.
We evaluated bleb fluid images taken after Baerveldt glaucoma implantation. T2-weighted images of bleb fluid were scanned with 3 Tesla magnetic resonance imaging in 52 patients who had undergone tube-shunt surgery using the 350-mm2 endplate Baerveldt glaucoma implant; three-dimensional images were constructed from these images. Bleb fluid images were classified into either a layer of bleb fluid on either side of the endplate (double bleb layer group; n=24) or one layer outside the endplate (single bleb layer group; n=28). Despite there being no correlation between the bleb volume and the postoperative IOP (r=−0.080; P=0.57), the double bleb layer group had significantly lower postoperative IOPs than the single bleb layer group (12.3±3.8mmHg vs. 14.7±4.1mmHg, respectively; P=0.033). The single bleb layer was significantly related to higher numbers of prior intraocular surgeries (relative risk=2.85; P=0.0014). Formation of a layer of bleb fluid on either side of the endplate may have resulted in the lower postoperative IOPs after Baerveldt glaucoma implantation. Repeated intraocular surgery adversely affects formation of the double bleb layer.
IWASAKI Kentaro (2020 graduated in fiscal year)

Doctoral Dissertation List

Study Support System

Please refer to “University of Fukui, Graduate School of Medical Sciences 2020” (Page 34) for details.

  • Various support systems are available for exemption or postponement of the admission fee and tuition fee. If you would like to apply for one, please contact the academic affairs office in Matsuoka Campus (+81-776-61-8265) before you start the enrollment process (pay the admission fee or tuition fee).
  • Various scholarship programs are available. If you would like to apply, please contact the academic affairs office in Matsuoka Campus (+81-776-61-8265) before you apply.

International Student Support

We offer the following support for international students to contribute to the facilitation of international exchange in education and research.

  1. Application for status of residence
  2. Dormitory
  3. Incentive scholarship for privately financed international students

Please refer to “University of Fukui, Graduate School of Medical Sciences 2020” (Page 35) for details.

Application Guidelines for Doctoral Programs in Graduate School of Medical Sciences


“Criteria for Evaluation of Doctoral Dissertations, Graduate School of Medical Sciences, University of Fukui”